What Are The Effects of Kratom on Kidneys; A Brief Overview.


It may be one of your major concerns whether using kratom is good or bad for your kidneys. The strain we put on our glandular organs over time can give rise to health problems and serious concerns.

If you are a regular kratom consumer, you should ask yourself a few questions like, Are there any side effects of kratom? And, How much of the herb can cause damage to any of your organs?

Firstly, it is important to know the association between these two, kratom and the kidney, in order to understand kratom’s effects on the kidneys. This article will help you to find all your concerns regarding kratom and its effects on the kidneys.

Kratom and Kidneys?

The botanical, named as Kratom, is an extract from the leaves of  Southeast Asian trees.  It is scientifically known as Mitragyna Speciosa Korth.

Click here to read about kratom and how it works: https://grhkratom.com/faq/what-is-kratom-and-how-does-kratom-work/  

The herb contains two alkaloids named Mitragynine and 7-hydroxymitragynine. These two mentioned alkaloids are responsible for all the effects of kratom. Many have used this medicinal herb as a cure for various diseases for decades.

Whereas the kidney is one of the paired organs in the body. It purifies our blood and body by removing excessive water and waste in the form of urine. Also, it balances the chemical levels present in the body.

What Role Do the Kidneys Play?

Except for the excretion of waste from the body, the kidneys produce such hormones, like renin, that help control blood pressure and also stimulate the bone marrow to generate red blood cells. Also, it regulates salts, potassium, and acid content in the body.

What Role Do the Kidneys Play

Kidney Damage Using Kratom:

In order to understand how our kidneys get affected by kratom, it is crucial to understand its connection with the liver. The liver and the kidneys are connected in such a way that if the liver gets affected and stops supplying blood to the kidneys properly, it can cause chronic kidney diseases.

In general, the occurrence of kidney failure in relation to Kratom typically takes place when the liver stops working properly, resulting in burdening the kidneys.

Consistent consumption of Kratom for over the years can cause indicative signs of acute kidney failure. As Kratom use increases bit by bit, medical professionals are becoming more aware of how it can contribute to the failure of the kidneys.

How is Kratom Metabolized and Excreted?

Enzymes like CYP3A4, CYP2D6, and CYP1A2 help to break down Kratom’s alkaloids. The liver mainly handles this process, and afterward, the body eliminates the waste through urine.

Kratom Toxicity and Kidney Failure:

The term refers to the harmful effects of kratom or symptoms that can occur when someone consumes excessive amounts of the herb or when it interacts negatively with other substances. Kratom toxicity can be a cause of different health problems and can result in life-threatening issues.

Kratom toxicity usually occurs after a high dose of the flora, i.e., 8g of the herb. Usually, the herb is not harmful to many, but in intensely severe and rare cases, it can be a cause of life threatening toxicities.

If you use the flora responsibly and only take what you need, then it is unlikely that you will harm your kidneys. Kidney damage is not something that happens right away, and there are usually warning signs that let you know if the botanical is causing a problem before it hurts your kidneys.

But if you take huge amounts of kratom for a long period of time it can hurt your kidneys. Generally, kratom affecting kidneys is not a frequent phenomenon, but it occurs normally in those who use excessive or large amounts of it consistently. 

Other Side Effects of Kratom:

It is important to ask yourself a question before using kratom, are there any other side effects of kratom, other than kidney failure?

It is imperative to be aware of potential side effects associated with the herb. There are many factors that influence the various side effects of this botanical, such as the specific type of the herb’s leaf can also affect the side effects experienced.

The various effects of this botanical and its symptoms include: 

  • Nausea and vomiting.
  • Drowsiness.
  • Agitation and/or aggression.
  • Itching.
  • Dizziness.
  • Sweating or chills.
  • Dry mouth.
  • Weight loss.
  • Loss of Appetite 
  • Muscle discomforting.
  • Rapid heartbeat.
  • Urination issues.
  • Constipation.
  • High blood pressure.

Other Side Effects of Kratom

Kratom Safety and Precautions:

To ensure safety while using kratom, it is important to ensure that you keep these points in mind:

  • Start with a low dosage and cautiously increase it if desired.
  • Use kratom responsibly and avoid excessive or prolonged use.
  • Stay hydrated by drinking plenty of water when using kratom.
  • Be aware of the possible reactions with the other medications or substances.
  • In the event of any pre-existing health conditions or concerns, it is advisable to seek the guidance of a healthcare professional.
  • Do not drive or operate any sort of heavy machinery after consuming kratom.
  • Keep the medicinal herb out of reach of children and pets.
  • Store kratom in a cool, dry place to maintain its potency.
  • It is advised to learn about potential hazards and adverse reactions associated with the consumption of kratom.
  • Stay informed about local regulations and the legality of the botanical in your area.

In order to prevent potential health issues such as kidney failure or liver damage associated with the flora, it is crucial to decrease any negative effects. Fortunately, following a few helpful suggestions can greatly reduce your chances of experiencing these issues.

Maintaining control over how much of the herb you take is crucial and will safeguard you from becoming obsessive. Additionally, trying different strains and using substances that enhance kratom effects can be beneficial.

Kratom Safety and Precautions

How to Monitor Kidney Health?

To monitor kidney health, it is essential to go through regular medical check-ups and screenings. These screenings often involve blood and urine tests that can detect any abnormalities in kidney functions.

In addition, maintaining a healthy lifestyle by drinking ample amount of water, avoiding excessive salt, spices, and sugar intake, exercising regularly, and managing persistent conditions like diabetes and high blood pressure can help promote kidney health and prevent possible potential issues.

It is important to consult a healthcare professional for personalized guidance on kidney health monitoring based on individual risk factors and medical history.


In general, the usage of kratom is thought to be reasonably secure for most people. Still, more research is needed to determine whether kratom’s impact on kidney health is advantageous or detrimental.

Some evidence put forward that it can potentially cause challenges for this organ, particularly when combined with certain medications that may cause concern.

It is advisable to seek guidance from a healthcare provider or medical professional before using kratom if you have concerns about its potential effects on your kidneys.


1: Is Kratom Legal and Safe to Use?

Answer: It’s prudent to review the particular regulations regarding the legality of kratom in your geographical location, as it can vary by country and region.

As for safety concerns, responsible use of kratom in moderate amounts is generally considered safe, but potential risks and side effects of kratom still exist.

2: How long do the effects of Kratom last in the body?

Answer: The length of time kratom remains detectable in the body can fluctuate based on multiple factors, including dosage, frequency of usage, metabolic rate, and individual variances.

On average, kratom traces are present in urine for up to five days. In addition, its effects typically last for about 5 to 6 hours.

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